GSK2838232
Cat. No.：YN250657
CAS No. ：1443460-91-0
| 产品名称: | GSK2838232 |
| CAS No.: | 1443460-91-0 |
| Chemical Name: | (3β)-3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-28-norlup-18-en-21-one |
| Synonyms: | |
| 分子量: | 809.56 |
| 分子式: | C₄₈H₇₃ClN₂O₆ |
| SMILES: | CC1(C)[C@@H](OC(CC(C)(C)C(O)=O)=O)CC[C@@]2(C)[C@@]1([H])CC[C@]3(C)[C@]2([H])CC[C@@]4([H])[C@@]3(C)CC[C@](C5)([C@H](CN(CCN(C)C)CC6=CC=C(Cl)C=C6)O)C4=C(C(C)C)C5=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK2838232 抑制HIV逆转录酶活性, 详细信息请参考专利文献WO/2013090664A1中的化合物51。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Johnson, M., Jewell, R.C., Peppercorn, A., et al.The safety, tolerability, and pharmacokinetic profile of GSK2838232, a novel 2nd generation HIV maturation inhibitor, as assessed in healthy subjectsPharmacol. Res. Perspect.6(4),e00408(2018)
Cihlar, T., and Fordyce, M.Current status and prospects of HIV treatmentCurr. Opin. Virol.18,50-56(2016)
