Etravirine
Cat. No.：YN250852
| 产品名称: | Etravirine |
| CAS No.: | 269055-15-4 |
| Chemical Name: | 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile |
| Synonyms: | 依曲韦林; R165335; TMC125 |
| 分子量: | 435.28 |
| 分子式: | C₂₀H₁₅BrN₆O |
| SMILES: | N#CC1=CC(C)=C(C(C)=C1)OC2=NC(NC3=CC=C(C=C3)C#N)=NC(N)=C2Br |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Etravirine 是一种非核苷逆转录酶抑制剂 (NNRTI)，具有抗 HIV 的作用。 |
| IC50和靶点: | |
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Andries, K., Azijn, H., Thielemans, T., et al.TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1Antimicrob. Agents Chemother.48(12),4680-4686(2004)
Figueiredo, A., Moore, K.L., Mak, J., et al.Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-PolPLoS Pathog.2(11),e119(2006)
