Lamivudine
Cat. No.：YN250969
| 产品名称: | Lamivudine |
| CAS No.: | 134678-17-4 |
| Chemical Name: | 4-amino-1-[(2R,5S)-2-(hydroxymethyl)1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone |
| Synonyms: | 拉米夫定; BCH-189 |
| 分子量: | 229.26 |
| 分子式: | C₈H₁₁N₃O₃S |
| SMILES: | O=C1N=C(N)C=CN1[C@@H]2CS[C@H](CO)O2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lamivudine (BCH-189) 是核苷逆转录酶抑制剂 (NRTIs)。Lamivudine (BCH-189) 可以抑制HIV逆转录酶1和2以及乙型肝炎病毒的逆转录酶。 |
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Johnson, M.A., Moore, K.H., Yuen, G.J., et al.Clinical pharmacokinetics of lamivudineClin. Pharmacokinet.36(1),41-66(1999)
Coates, J.A., Cammack, N., Jenkinson, H.J., et al.(–)-2'-Deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitroAntimicrob. Agents Chemother.36(4),733-739(1992)
Mason, W.S., Cullen, J., Moraleda, G., et al.Lamivudine therapy of WHV-infected woodchucksVirology245(1),18-32(1998)
