Sulfadoxine
Cat. No.：YN251043
| 产品名称: | Sulfadoxine |
| CAS No.: | 2447-57-6 |
| Chemical Name: | 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamide |
| Synonyms: | 磺胺多辛; Sulphadoxine |
| 分子量: | 310.33 |
| 分子式: | C₁₂H₁₄N₄O₄S |
| SMILES: | O=S(NC1=NC=NC(OC)=C1OC)(C2=CC=C(N)C=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sulfadoxine(Sulphadoxine)是长效的磺胺类化合物，常与pyrimethamine结合起到抗疟疾作用。Sulfadoxine 抑制HIV在外周血单核细胞中的复制。 |
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Brooks, D.R., Wang, P., Read, M., et al.Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxineEur. J. Biochem.224(2),397-405(1994)
Hyde, J.E.Exploring the folate pathway in Plasmodium falciparumActa. Trop.94(3),191-206(2005)
Wang, P., Read, M., Sims, P.F.G., et al.Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization.Mol. Microbiol.23(5),979-986(1997)
