Bevirimat
Cat. No.：YN251539
| 产品名称: | Bevirimat |
| CAS No.: | 174022-42-5 |
| Chemical Name: | (3β)-3-(3-carboxy-3-methyl-1-oxobutoxy)-lup-20(29)-en-28-oic acid |
| Synonyms: | 贝韦立马; PA-457; MPC-4326; YK FH312 |
| 分子量: | 584.83 |
| 分子式: | C₃₆H₅₆O₆ |
| SMILES: | OC([C@]1(CC[C@H]2C(C)=C)[C@@]2([H])[C@](CC[C@@]3([H])[C@]4(CC[C@]5([H])[C@@]3(CC[C@H](OC(CC(C)(C)C(O)=O)=O)C5(C)C)C)C)([H])[C@@]4(C)CC1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bevirimat (PA-457; MPC-4326; YK FH312) 是HIV-1病毒颗粒成熟抑制剂。 |
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Martin, D.E., Salzwedel, K., and Allaway, G.P.Bevirimat: A novel maturation inhibitor for the treatment of HIV-1 infectionAntivir. Chem. Chemother.19(3),107-113(2008)
Wang, D., Lu, W., and Li, F.Pharmacological intervention of HIV-1 maturationActa Phatm. Sin. B5(6),493-499(2015)
Li, F., Goila-Gaur, R., Salzwedel, K., et al.PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processingProc. Natl. Acad. Sci. USA100(23),13555-13560(2003)
Soddart, C.A., Joshi, P., Sloan, B., et al.Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv micePLoS One2(11),e1251(2007)
