Corydine
Cat. No.：YN251613
| 产品名称: | Corydine |
| CAS No.: | 476-69-7 |
| Chemical Name: | 5,6,6aS,7-tetrahydro-2,10,11-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-1-ol |
| Synonyms: | 紫堇定 |
| 分子量: | 341.40 |
| 分子式: | C₂₀H₂₃NO₄ |
| SMILES: | OC1=C(OC)C=C2C3=C1C(C(OC)=C(OC)C=C4)=C4C[C@]3([H])N(CC2)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Corydine 是一种天然存在的生物碱，可从Croton echinocarpus叶子中提取。Corydine 有效抑制逆转录酶 (reverse transcriptase，RT) 活性，IC50为 356.8 μg/mL。Corydinez 在体外具有抗HIV潜力，浓度为 450 μg/mL 时抑制 40% 的 HIV-1 逆转录酶活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kondo, Y., Imai, Y., Hojo, H., et al.Suppression of tumor cell growth and mitogen response by aporphine alkaloids, dicentrine, glaucine, corydine, and apomorphineJ. Pharmacobiodyn.13(7),426-431(1990)
Kaserer, T., Steinacher, T., Kainhofer, R., et al.Identifcation and characterization of plant‑derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonistsSci. Rep.10(1),13804(2020)
del Rayo Camacho, M., Kirby, G.C., Warhurst, D.C., et al.Oxoaporphine alkaloids and quinones from Stephania dinklagei and evaluation of their antiprotozoal activitiesPlanta Med.66(5),478-480(2000)
