OICR-9429
Cat. No.：YN310303
CAS No. ：1801787-56-3
| 产品名称: | OICR-9429 |
| CAS No.: | 1801787-56-3 |
| Chemical Name: | N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide |
| Synonyms: | OICR 9429 |
| 分子量: | 555.59 |
| 分子式: | C₂₉H₃₂F₃N₅O₃ |
| SMILES: | O=C(C1=CNC(C=C1C(F)(F)F)=O)NC2=CC(C3=CC(CN4CCOCC4)=CC=C3)=CC=C2N5CCN(C)CC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | OICR-9429是一个新颖的相互作用的小分子Wdr5-MLL拮抗剂，IC50是5 uM，能够抑制增殖。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Migliori, V., Mapelli, M., and Guccione, E.On WD40 proteins: Propelling our knowledge of transcriptional control?Epigenetics7(8),815-822(2012)
Guccione, E., Bassi, C., Casadio, F., et al.Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusiveNature449(7164),933-937(2007)
Guelman, S., Kozuka, K., Mao, Y., et al.The double-histone-acetyltransferase complex ATAC is essential for mammalian developmentMol. Cell. Biol.29(5),1176-1188(2009)
