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Rimantadine hydrochloride

Cat. No.:YN251014

  • CAS No. :1501-84-4

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    • 参考文献
    • 产品名称: Rimantadine hydrochloride
      CAS No.: 1501-84-4
      Chemical Name: α-methyl-tricyclo[3.3.1.13,7]decane-1-methanamine, monohydrochloride
      Synonyms:盐酸金刚乙胺
      分子量:215.76
      分子式:C₁₂H₂₂ClN
      SMILES:CC(C1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)N.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Rimantadine hydrochloride 盐酸盐是口服抗流感病毒A化合物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Bean, B.Antiviral therapy: Current concepts and practicesClin. Microbiol. Rev.5(2),146-182(1992)

      Wang, J., Ma, C., Wang, J., et al.Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virusJ. Med. Chem.56(7),2804-2812(2013)

      Breitinger, U., Farag, N.S., Ali, N.K.M., et al.Patch-clamp study of hepatitis C p7 channels reveals genotype-specific sensitivity to inhibitorsBiophys J.110(11),2419-2429(2016)

      Rey-Carrizo, M., Torres, E., Ma, C., et al.3-Azatetracyclo[5.2.1.15,8.01,5]undecane derivatives: From wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutantJ. Med. Chem.56(22),9265-9274(2013)

      Rabinovich, S.Rimantadine therapy of influenza A infection in miceAntimicrob. Agents Chemother.1(5),408-411(1972)

      Kelly, J.M., Miles, M.A., and Skinner, A.C.The anti-influenza virus drug rimantadine has trypanocidal activityAntimicrob. Agents Chemother.43(4),985-987(1999)

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