Nelfinavir Mesylate
Cat. No.：YN372279
CAS No. ：159989-65-8
| 产品名称: | Nelfinavir Mesylate |
| CAS No.: | 159989-65-8 |
| Chemical Name: | (3S,4aS,8aS)-N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide, monomethanesulfonate |
| Synonyms: | AG 1343 Mesylate |
| 分子量: | 663.89 |
| 分子式: | C₃₃H₄₉N₃O₇S₂ |
| SMILES: | [H][C@]12C[C@@H](C(NC(C)(C)C)=O)N(C[C@H]([C@@H](NC(C3=C(C)C(O)=CC=C3)=O)CSC4=CC=CC=C4)O)C[C@@]1([H])CCCC2.CS(=O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nelfinavir Mesylate (AG 1343 Mesylate) 是一种有效的口服生物可利用的HIV-1蛋白酶抑制剂 (Ki=2 nM)，用于 HIV感染。Nelfinavir Mesylate (AG 1343 Mesylate) 是一种广谱的抗癌剂。 |
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Kaldor, S.W., Kalish, V.J., Davies, J.F., II, et al.Viracept (nelfinavir mesylate, AG1343): A potent, orally bioavailable inhibitor of HIV-1 proteaseJ. Med. Chem.40(24),3979-3985(1997)
Shim, J.S., Rao, R., Beebe, K., et al.Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavirJ. Natl. Cancer Inst.104(20),1576-1590(2012)
