Saquinavir Mesylate
Cat. No.：YN372422
CAS No. ：149845-06-7
| 产品名称: | Saquinavir Mesylate |
| CAS No.: | 149845-06-7 |
| Chemical Name: | (2S)-N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-butanediamide, monomethanesulfonate |
| Synonyms: | 沙奎那韦甲磺酸盐; Ro 31-8959/003 |
| 分子量: | 766.95 |
| 分子式: | C₃₉H₅₄N₆O₈S |
| SMILES: | NC(C[C@H](C(N[C@@H](CC1=CC=CC=C1)C(CN2C[C@@]3([H])CCCC[C@]3(C[C@H]2C(NC(C)(C)C)=O)[H])O)=O)NC(C4=NC5=CC=CC=C5C=C4)=O)=O.CS(O)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Saquinavir Mesylate (Ro 31-8959/003) 是HIV蛋白酶抑制剂，用于逆转录病毒研究。 |
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Roberts, N.A., Martin, J.A., Kinchington, D., et al.Rational design of peptide-based HIV proteinase inhibitorsScience248(4953),358-361(1990)
Stefanidou, M., Herrera, C., Armanasco, N., et al.Saquinavir inhibits early events associated with establishment of HIV-1 infection: Potential role for protease inhibitors in preventionAntimicrob. Agents Chemother.56(8),4381-4390(2012)
Chiou, W.-C., Hsu, M.-S., Chen, Y.-T., et al.Repurposing existing drugs: Identification of SARS-CoV-2 3C-like protease inhibitorsJ. Enzyme Inhib. Med. Chem.36(1),147-153(2021)
