Amprenavir
Cat. No.:YN372436
产品名称: | Amprenavir |
CAS No.: | 161814-49-9 |
Chemical Name: | N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid, (3S)-tetrahydro-3-furanyl ester |
Synonyms: | 安瑞那韦; VX-478 |
分子量: | 505.63 |
分子式: | C₂₅H₃₅N₃O₆S |
SMILES: | O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](O)CN(S(=O)(C3=CC=C(N)C=C3)=O)CC(C)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Amprenavir (VX-478) 是HIV蛋白酶抑制剂,Ki为0.6 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Sherrill, R.G., Furfine, E.S., Hazen, R.J., et al.Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitorsBioorg. Med. Chem. Lett.15(15),3560-3564(2005)