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Indinavir sulfate

Cat. No.:YN372841

  • CAS No. :157810-81-6

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Indinavir sulfate
      CAS No.: 157810-81-6
      Chemical Name: 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide, monosulfate
      Synonyms:硫酸茚地那韦; MK-639 sulfate; L735524 sulfate
      分子量:711.87
      分子式:C₃₆H₄₉N₅O₈S
      SMILES:O=C([C@@H](C[C@H](O)CN(CCN(CC1=CN=CC=C1)C2)[C@@H]2C(NC(C)(C)C)=O)CC3=CC=CC=C3)N[C@H]4C(C=CC=C5)=C5C[C@H]4O.O=S(O)(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Indinavir(MK-639; L735524)硫酸盐是HIV蛋白酶抑制剂,具有很好的口服生物相容性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Vacca, J.P., Dorsey, B.D., Schleif, W.A., et al.L-735,524: An orally bioavailable human immunodeficiency virus type 1 protease inhibitorProc. Natl. Acad. Sci. USA91(9),4096-4100(1994)

      Dorsey, B.D., McDonough, C., McDaniel, S.L., et al.Identification of MK-944a: A second clinical candidate from the hydroxylaminepentanamide isostere series of HIV protease inhibitorsJ. Med. Chem.43(18),3386-3399(2000)

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