Pepstatin
Cat. No.：YN373431
| 产品名称: | Pepstatin |
| CAS No.: | 26305-03-3 |
| Chemical Name: | N-(3-methyl-1-oxobutyl)-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide |
| Synonyms: | 抑肽素; |
| 分子量: | 685.89 |
| 分子式: | C₃₄H₆₃N₅O₉ |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pepstatin (Pepstatin A) 是由放线菌类产生的一种特异性的天冬氨酸蛋白酶 (aspartic proteases) 抑制剂，能够抑制 hemoglobin-pepsin，hemoglobin-proctase，casein-pepsin，casein-proctase，casein-acid protease 和 hemoglobin-acid protease 的活性，IC50值分别为 4.5 nM，6.2 nM，150 nM，290 nM，520 nM 和 260 nM；同时可抑制 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Umezawa, H., Aoyagi, T., Morishima, H., et al.Pepstatin, a new pepsin inhibitor produced by actinomycetesJ. Antibiot. (Tokyo)23(5),259-262(1970)
Sarubbi, E., Seneci, P.F., Angelastro, M.R., et al.Peptide aldehydes as inhibitors of HIV proteaseFEBS Lett.319(3),253-256(1993)
Eid, M., Evin, G., Castro, B., et al.New renin inhibitors homologous with pepstatinBiochem. J.197(2),465-471(1981)
Isahara, K., Ohsawa, Y., Kanamori, S., et al.Regulation of a novel pathway for cell death by lysosomal aspartic and cysteine proteinasesNeuroscience91(1),233-249(1999)
