Arimoclomol maleate
Cat. No.：YN370334
CAS No. ：289893-26-1
| 产品名称: | Arimoclomol maleate |
| CAS No.: | 289893-26-1 |
| Chemical Name: | N-{[(2R)-2-Hydroxy-3-piperidin-1-ylpropyl]oxy}pyridine-3-carboximidoyl Chloride 1-Oxide (2Z)-2-butenedioate; BRX 220 |
| Synonyms: | BRX-220 |
| 分子量: | 429.85 |
| 分子式: | C₁₈H₂₄ClN₃O₇ |
| SMILES: | Cl/C(C1=C[N+]([O-])=CC=C1)=N\OC[C@H](O)CN2CCCCC2.OC(/C=C\C(O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。Arimoclomol 通过增强 Hsp 表达来保护运动神经元，从而通过泛素-蛋白酶体系统直接影响蛋白质聚集及清除错误折叠和装配的蛋白。 |
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Kurthy, M., et al.: New. York. Acad. Sci., 967, 482 (2002)
Kalmar, B., et al.: Exp. Neurol., 184, 636 (2003)
