KW-2478
Cat. No.：YN371557
CAS No. ：819812-04-9
| 产品名称: | KW-2478 |
| CAS No.: | 819812-04-9 |
| Chemical Name: | 2-ethyl-3,5-dihydroxy-N,N-bis(2-methoxyethyl)-6-[3-methoxy-4-[2-(4-morpholinyl)ethoxy]benzoyl]-benzeneacetamide |
| Synonyms: | KW2478 |
| 分子量: | 574.66 |
| 分子式: | C₃₀H₄₂N₂O₉ |
| SMILES: | O=C(N(CCOC)CCOC)CC1=C(C(C2=CC=C(OCCN3CCOCC3)C(OC)=C2)=O)C(O)=CC(O)=C1CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KW-2478 是一种Hsp90α抑制剂，IC50值为 3.8 nM，对多种人类血液肿瘤细胞具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"HSP90α:3.8 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Nakashima, T., Ishii, T., Tagaya, H., et al.New molecular and biological mechanism of antitumor activities of KW-2478, a novel nonansamycin heat shock protein 90 inhibitor, in multiple myeloma cellsClin. Cancer Res.16(10),2792-2802(2010)
