Tamoxifen
Cat. No.：YN371784
| 产品名称: | Tamoxifen |
| CAS No.: | 10540-29-1 |
| Chemical Name: | 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine |
| Synonyms: | 他莫昔芬; ICI 47699; (Z) |
| 分子量: | 371.51 |
| 分子式: | C₂₆H₂₉NO |
| SMILES: | CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tamoxifen (ICI 47699) 是一种口服有效的，选择性雌激素受体 (estrogen receptor) 调节剂 (SERM)，可阻断乳腺细胞中的雌激素作用，并可激活其他细胞，如骨骼，肝脏和子宫细胞中的雌激素活性。Tamoxifen 是一种有效的Hsp90激活剂，可增强 Hsp90 分子伴侣 ATPase 的活性。Tamoxifen 还可以有效抑制传染性EBOV Zaire和Marburg (MARV)，IC50分别为 0.1 µM 和 1.8 µM。Tamoxifen 可以激活自噬 (au |
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Mazzarino, M., Braganò, M.C., de la Torre, X., et al.Relevance of the selective oestrogen receptor modulators tamoxifen, toremifene and clomiphene in doping field: Endogenous steroids urinary profile after multiple oral dosesSteroids76(12),1400-1406(2011)
Seehusen, D.A., and Glorioso, J.E.Tamoxifen as an ergogenic agent in women body buildersClin. J. Sport Med.12(5),313-314(2002)
Agency, W.A.-D.2014 Anti-doping testing figures report,(2014)
