VER-49009
Cat. No.：YN372372
CAS No. ：558640-51-0
| 产品名称: | VER-49009 |
| CAS No.: | 558640-51-0 |
| Chemical Name: | 3-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide |
| Synonyms: | CCT 129397 |
| 分子量: | 387.82 |
| 分子式: | C₁₉H₁₈ClN₃O₄ |
| SMILES: | O=C(C1=NNC(C2=CC(Cl)=C(O)C=C2O)=C1C3=CC=C(OC)C=C3)NCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VER-49009 是一种Hsp90抑制剂，IC50值为 25 nM，Kd值为 78 nM。 |
| IC50和靶点: | [{name:"HSP90:25 nM (IC50)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sharp, S.Y., Prodromou, C., Boxall, K., et al.Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analoguesMol. Cancer Ther.6(4),1198-1211(2007)
