Amenamevir
Cat. No.:YN250599
CAS No. :841301-32-4
产品名称: | Amenamevir |
CAS No.: | 841301-32-4 |
Chemical Name: | N-(2,6-dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide, 1,1-dioxide |
Synonyms: | 阿莫奈韦; ASP2151 |
分子量: | 482.55 |
分子式: | C₂₄H₂₆N₄O₅S |
SMILES: | O=C(C(CC1)CCS1(=O)=O)N(C2=C(C)C=CC=C2C)CC(NC3=CC=C(C4=NOC=N4)C=C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Amenamevir 是一种helicase-primase抑制剂,对HSVs具有强效的抗病毒活性,EC50值为 14 ng/mL。 |
IC50和靶点: | [{name:"HSV-1:7.7-20 ng/mL (IC50)"},{name: "HSV-2:15-58 ng/mL (IC50)"}] |
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Chono, K., Katsumata, K., Kontani, T., et al.ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2J. Antimicrob. Chemother.65(8),1733-1741(2010)