Penciclovir
Cat. No.：YN250717
| 产品名称: | Penciclovir |
| CAS No.: | 39809-25-1 |
| Chemical Name: | 2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one |
| Synonyms: | 喷昔洛韦; BRL 39123; VSA 671 |
| 分子量: | 253.26 |
| 分子式: | C₁₀H₁₅N₅O₃ |
| SMILES: | O=C1NC(N)=NC2=C1N=CN2CCC(CO)CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Penciclovir 有效作用于HSV1 和 2，IC50分别为 0.04-1.8 μg/mL 和 0.06-4.4 μg/mL。 |
| IC50和靶点: | [{name:"HSV-1:0.5 μg/mL (EC50)"},{name: "HSV-2:0.8 μg/mL (EC50)"}] |
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Boyd, M.R., Bacon, T.H., Sutton, D., et al.Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell cultureAntimicrob. Agents and Chemother.31(8),1238-1242(1987)
Hodge, R.A., and Perkins, R.M.Mode of action of 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine (BRL 39123) against herpes simplex virus in MRC-5 cellsAntimicrob. Agents and Chemother.33(2),223-229(1989)
Boyd, M.R., Bacon, T.H., and Sutton, D.Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxymethylbut-1-yl) guanine (BRL 39123) in animalsAntimicrob. Agents Chemother.32(3),358-363(1988)
