Famciclovir
Cat. No.:YN250720
产品名称: | Famciclovir |
CAS No.: | 104227-87-4 |
Chemical Name: | 2-[2-(2-amino-9H-purin-9-yl)ethyl]-1,3-propanediol, 1,3-diacetate |
Synonyms: | 泛昔洛韦; BRL 42810 |
分子量: | 321.33 |
分子式: | C₁₄H₁₉N₅O₄ |
SMILES: | NC1=NC=C2N=CN(CCC(COC(C)=O)COC(C)=O)C2=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Famciclovir(BRL 42810)是鸟嘌呤类似物,具有抗疱疹病毒活性。 |
IC50和靶点: | |
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Hodge, R.A.V.Famciclovir and penciclovir. The mode of action of famciclovir including its conversion to penciclovirAntivir. Chem. Chemother.4(2),67-84(1993)
Rashidi, M.R., Smith, J.A., Clarke, S.E., et al.In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liverDrug Metab. Dispos.25(7),805-813(1997)
Filer, C.W., Ramji, J.V., Allen, G.D., et al.Metabolic and pharmacokinetic studies following oral administration of famciclovir to the rat and dogXenobiotica.25(5),477-490(1995)