Trifluridine
Cat. No.:YN250857
产品名称: | Trifluridine |
CAS No.: | 70-00-8 |
Chemical Name: | α,α,α-trifluoro-thymidine |
Synonyms: | 曲氟尿苷; Trifluorothymidine; 5-Trifluorothymidine; TFT |
分子量: | 296.20 |
分子式: | C₁₀H₁₁F₃N₂O₅ |
SMILES: | O=C1C(C(F)(F)F)=CN([C@@H]2O[C@H](CO)[C@@H](O)C2)C(N1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Trifluridine (Trifluorothymidine; 5-Trifluorothymidine; TFT) 是不可逆的胸苷酸合酶抑制剂,从而抑制DNA合成。Trifluridine 是用于单纯疱疹病毒 (HSV) 感染的抗病毒药物。 |
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Suzuki, N., Emura, T., and Fukushima, M.Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymesInt. J. Oncol.39(1),263-270(2011)