CHR-6494
Cat. No.:YN290338
CAS No. :1333377-65-3
产品名称: | CHR-6494 |
CAS No.: | 1333377-65-3 |
Chemical Name: | 3-(1H-indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine |
Synonyms: | CHR-6494;3-(1H-Indazol-5-yl)-N-propylimidazo-[1,2-b]pyridazin-6-amine;3-?(1H-?indazol-?5-?yl)?-?N-?propyl-Imidazo[1,?2-?b]?pyridazin-?6-?amine;CHR-6494 trifluoroacetate salt;CHR 6494 |
分子量: | 292.34 |
分子式: | C₁₆H₁₆N₆ |
SMILES: | CCCNC(C=C1)=NN2C1=NC=C2C3=CC(C=NN4)=C4C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CHR-6494 是一种有效的haspin抑制剂,能够抑制组蛋白 H3T3 的磷酸化,IC50值为 2 nM。 |
IC50和靶点: | [{name:"haspin:2 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Huertas, D., Soler, M., Moreto, J., et al.Antitumor activity of a small-molecule inhibitor of the histone kinase HaspinOncogene,1-11(2011)