Ciliobrevin A
Cat. No.：YN450012
CAS No. ：302803-72-1
规格
价格(RMB)
库存
| 产品名称: | Ciliobrevin A |
| CAS No.: | 302803-72-1 |
| Chemical Name: | 2,4-dichloro-α-(3,4-dihydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo-benzenepropanenitrile |
| Synonyms: | HPI-4 |
| 分子量: | 358.18 |
| 分子式: | C₁₇H₉Cl₂N₃O₂ |
| SMILES: | N#C/C(C(C1=CC=C(Cl)C=C1Cl)=O)=C(N2)\NC3=C(C=CC=C3)C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ciliobrevin A 是一种Hedgehog(Hh) 信号通路抑制剂，平均抑制浓度 (IC50) 值小于 10 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Firestone, A.J., Weinger, J.S., Maldonado, M., et al.Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dyneinNature484(7392),125-129(2012)
Clippinger, A.J., and Alwaine, J.C.Dynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cellsGenes Dev.26(18),2015-2026(2012)
