Vismodegib
Cat. No.:YN450024
产品名称: | Vismodegib |
CAS No.: | 879085-55-9 |
Chemical Name: | |
Synonyms: | 维莫德吉; GDC-0449 |
分子量: | 421.30 |
分子式: | C₁₉H₁₄Cl₂N₂O₃S |
SMILES: | O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Vismodegib (GDC-0449) 是一种具有口服活性的hedgehog抑制剂,IC50值为 3 nM;还可抑制P-gp和ABCG2的活性,IC50值分别为 3.0 μM 和 1.4 μM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |