JK184
Cat. No.：YN450077
CAS No. ：315703-52-7
规格
价格(RMB)
库存
| 产品名称: | JK184 |
| CAS No.: | 315703-52-7 |
| Chemical Name: | N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine |
| Synonyms: | N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine;Hh Signaling Antagonist VII, JK184;JK 184;JK184 (Hh Signaling Antagonist VII);N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine;N-(4-Ethoxyphenyl)-4-(2-me |
| 分子量: | 350.44 |
| 分子式: | C₁₉H₁₈N₄OS |
| SMILES: | CC1=C(C2=CSC(NC3=CC=C(OCC)C=C3)=N2)N4C=CC=CC4=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JK184 是一种有效的Hedgehog (Hh)抑制剂，在哺乳动物细胞中，IC50为 30 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Lee, J., Wu, X., Pasca de Magliano, M., et al.A small-molecule antagonist of the hedgehog signaling pathwayChembiochem8(16),1916-1919(2007)
Cupido, T., Rack, P.G., Firestone, A.J., et al.The imidazopyridine derivative JK184 reveals dual roles for microtubules in hedgehog signalingAngew. Chem. Int. Ed. Engl.48(13),2321-2324(2009)
