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N-Acetylhistamine

Cat. No.:YN320449

  • CAS No. :673-49-4

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    • 产品名称: N-Acetylhistamine
      CAS No.: 673-49-4
      Chemical Name: N-[2-(1H-imidazol-5-yl)ethyl]-acetamide
      Synonyms:N-Omega-acetylhistamine
      分子量:153.18
      分子式:C₇H₁₁N₃O
      SMILES:CC(NCCC1=CN=CN1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: N-Acetylhistamine 是一种组胺代谢物。N-acetylhistamine 可用作过敏反应中组氨酸代谢的生物标志物。
      IC50和靶点:
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    • Dempsey, D.R., Jeffries, K.A., Handa, S., et al.Mechanistic and structural analysis of a Drosophila melanogaster enzyme, arylalkylamine N-acetyltransferase Like 7, an enzyme that catalyzes the formation of N-acetylarylalkylamides and N-acetylhistamineBiochemistry54(16),2644-2658(2015)

      Field, R.A., Haines, A.H., Chrystal, E.J.T., et al.Histidines, histamines and imidazoles as glycosidase inhibitorsBiochem J.274(Pt 3),885-889(1991)

      Schilling, S., Niestroj, A.J., Rahfeld, J.-U., et al.Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelatorsJ. Biol. Chem.278(50),49773-49779(2003)

      Turnbull, L.W., and Kay, A.B.Eosinophils and mediators of anaphylaxis. Histamine and imidazole acetic acid as chemotactic agents for human eosinophil leucocytesImmunology31(5),797-802(1976)

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