Pitolisant hydrochloride
Cat. No.：YN320562
CAS No. ：903576-44-3
| 产品名称: | Pitolisant hydrochloride |
| CAS No.: | 903576-44-3 |
| Chemical Name: | 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine, monohydrochloride |
| Synonyms: | Ciproxidine; BF 2649 |
| 分子量: | 332.31 |
| 分子式: | C₁₇H₂₇Cl₂NO |
| SMILES: | ClC(C=C1)=CC=C1CCCOCCCN2CCCCC2.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pitolisant盐酸盐(BF2.649;Ciproxidine)是新型的人重组H3受体选择性反向激动剂，Ki为0.16 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ligneau, X., Perrin, D., Landais, L., et al.BF2.649 [1-{3-[3-(4-chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacologyJ. Pharmacol. Exp. Ther.320(1),365-375(2007)
Brabant, C., Charlier, Y., and Tirelli, E.The histamine H₃-receptor inverse agonist pitolisant improves fear memory in miceBehav. Brain Res.243,199-204(2013)
