PF-03654764
Cat. No.：YN320587
| 产品名称: | PF-03654764 |
| CAS No.: | 935840-35-0 |
| Chemical Name: | |
| Synonyms: | PF 3654764 |
| 分子量: | 350.45 |
| 分子式: | C₂₀H₂₈F₂N₂O |
| SMILES: | O=C([C@@H]1C[C@@](C2=CC(F)=C(CN3CCCC3)C=C2)(F)C1)NCC(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-03654764 是一种具有口服活性的，选择性组胺H3受体拮抗剂，对人 H3和大鼠 H3的Ki值分别为 1.2 nM 和 7.9 nM。PF-03654764 和 Fexofenadine (HY-B0801A) 组合具有用于过敏性鼻炎研究的潜力。 |
| IC50和靶点: | [{name:"human H3 receptor:1.2 nM (Ki)"},{name: "rat H3 receptor:7.9 nM (Ki)"},{name: "human H3 receptor:8.98 (pKi)"},{name: "rat H3 receptor:8.10 (pKi)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
