Rupatadine Fumarate
Cat. No.：YN320745
| 产品名称: | Rupatadine Fumarate |
| CAS No.: | 182349-12-8 |
| Chemical Name: | 8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, (2E)-2-butenedioate |
| Synonyms: | 富马酸卢帕他定; UR-12592 Fumarate |
| 分子量: | 532.03 |
| 分子式: | C₃₀H₃₀ClN₃O₄ |
| SMILES: | CC1=CN=CC(CN2CC/C(CC2)=C3C4=CC=C(Cl)C=C4CCC5=CC=CN=C5\3)=C1.O=C(O)/C=C/C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rupatadine Fumarate (UR-12592 Fumarate) 富马酸盐是PAF/H1受体双抑制剂，Ki值分别为0.55 μM 和 0.1 μM。 |
| IC50和靶点: | [{name:"H1 Receptor:0.1 μM (Ki)"},{name: "PAF:0.55 μM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Merlos, M., Giral, M., Balsa, D., et al.Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF)J. Pharmacol. Exp. Ther.280(1),114-121(1997)
