Lodoxamide
Cat. No.：YN320842
CAS No. ：53882-12-5
| 产品名称: | Lodoxamide |
| CAS No.: | 53882-12-5 |
| Chemical Name: | 2,2'-[(2-chloro-5-cyano-1,3-phenylene)diimino]bis[2-oxo-acetic acid] |
| Synonyms: | U-42585E free acid |
| 分子量: | 311.63 |
| 分子式: | C₁₁H₆ClN₃O₆ |
| SMILES: | OC(C(NC1=C(Cl)C(NC(C(O)=O)=O)=CC(C#N)=C1)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lodoxamide (U-42585E free acid) 是作为肥大细胞稳定剂的抗过敏化合物, 用于研究哮喘和过敏性结膜炎。 |
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MacKenzie, A.E., Caltabiano, G., Kent, T.C., et al.The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35Mol. Pharmacol.85(1),91-104(2014)
Johnson, H.G., and Sheridan, A.Q.The characterization of lodoxamide, a very active inhibitor of mediator release, in animal and human models of asthmaAgents Actions18(3-4),301-305(1986)
Yanni, J.M., Weimer, L.K., Glaser, R.L., et al.Effect of lodoxamide on in vitro and in vivo conjunctival immediate hypersensitivity responses in ratsInt. Arch. Allergy. Immunol.101(1),102-106(1993)
Bayer, A., Uludağ, H.A., Sobaci, G., et al.Comparison of antiallergic drugs in an experimental model of ocular anaphylaxisOphthalmologica217(2),119-123(2003)
