Cimetidine
Cat. No.：YN320843
| 产品名称: | Cimetidine |
| CAS No.: | 51481-61-9 |
| Chemical Name: | N-cyano-N''-methyl-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-guanidine |
| Synonyms: | 西咪替丁; SKF-92334 |
| 分子量: | 252.34 |
| 分子式: | C₁₀H₁₆N₆S |
| SMILES: | CC1=C(CSCC/N=C(NC)/NC#N)NC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cimetidine (SKF-92334) 是一种口服有效的，可逆的组胺H2受体拮抗剂，Ki为 0.6 μM。Cimetidine 也是一种反向激动剂。Cimetidine 具有抗癌和抗炎活性。 |
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Smit, M.J., Leurs, R., Alewijnse, A.E., et al.Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptorsProc. Natl. Acad. Sci. USA93(13),6802-6807(1996)
Lin, T.M., Evans, D.C., Warrick, M.W., et al.Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogsJ. Pharmacol. Exp. Ther.239(2),406-410(1986)
Natori, T., Sata, M., Nagai, R., et al.Cimetidine inhibits angiogenesis and suppresses tumor growthBiomed. Pharmacother.59(1-2),56-60(2005)
