Ciproxifan maleate
Cat. No.：YN320960
| 产品名称: | Ciproxifan maleate |
| CAS No.: | 184025-19-2 |
| Chemical Name: | cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxy]phenyl]-methanone (2Z)-2-butenedioate |
| Synonyms: | FUB 359 maleate |
| 分子量: | 386.40 |
| 分子式: | C₂₀H₂₂N₂O₆ |
| SMILES: | O=C(C1CC1)C2=CC=C(OCCCC3=CNC=N3)C=C2.O=C(O)/C=C\C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ciproxifan maleate (FUB 359 maleate) 是一种有效的，选择性的，具有口服活性和竞争性的组胺H3受体拮抗剂，IC50值为 9.2 nM。Ciproxifan maleate 对其他受体亚型的表观亲和力低。Ciproxifan maleate 可用于研究衰老性疾病和阿尔兹海默症。 |
| IC50和靶点: | [{name:"H3 receptor:9.2 nM (IC50)"}] |
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| Solvent & Solubility: |
Ligneau, X., Lin, J., Vanni-Mercier, G., et al.Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonistJ. Pharmacol. Exp. Ther.287(2),658-666(1998)
