Alcaftadine
Cat. No.：YN321110
CAS No. ：147084-10-4
| 产品名称: | Alcaftadine |
| CAS No.: | 147084-10-4 |
| Chemical Name: | 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-imidazo[2,1-b][3]benzazepine-3-carboxaldehyde |
| Synonyms: | 阿卡他定; R89674 |
| 分子量: | 307.39 |
| 分子式: | C₁₉H₂₁N₃O |
| SMILES: | O=CC1=CN=C2N1CCC3=CC=CC=C3/C2=C4CCN(C)CC\4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Alcaftadine (R89674) 是一种组胺H1受体拮抗剂，用于预防过敏性结膜炎引起的眼睛刺激。Alcaftadine 是一种广谱抗组胺剂，对组胺H1和H2受体具有高亲和力，而对H4受体具有较低的亲和力。Alcaftadine 还具有调节免疫细胞募集和肥大细胞稳定的作用。 |
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Gallois-Bernos, A.C., and Thurmond, R.L.Alcaftadine, a new antihistamine with combined antagonist activity at histamine H1, H2, and H4 receptorsJ. Receptor Ligand Channel Res.5,9-20(2012)
Ackerman, S., Smith, L.M., and Gomes, P.J.Ocular itch associated with allergic conjunctivitis: Latest evidence and clinical managementTher. Adv. Chronic Dis.7(1),52-67(2016)
Mahvan, T.D., Buckley, W.A., and Hornecker, J.R.Alcaftadine for the prevention of itching associated with allergic conjunctivitisAnn. Pharmacother.46,1025-1032(2012)
