Cetirizine D4
Cat. No.:YN321115
产品名称: | Cetirizine D4 |
CAS No.: | 1219803-84-5 |
Chemical Name: | [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-d4]acetic Acid Dihydrochloride; Alercet-d4; Alerid-d4; Alerlisin-d4; Cesta-d4; Cetiriz-d4; Cetirizine-d4 Dihydrochloride; Cetirizine-d4 Hydrochloride; Cetrak-d4; Cetrine-d4; Cetrizet-d4; Cistamine- |
Synonyms: | |
分子量: | 392.91 |
分子式: | C₂₁H₂₁D₄ClN₂O₃ |
SMILES: | O=C(O)COC([2H])([2H])C([2H])([2H])N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Cetirizine D4 是Cetirizine 的氘代物。Cetirizine 是羟嗪的羧化代谢物,是第二代抗组胺药。Cetirizine 是一种特异的、口服有效的、H1 受体的长效拮抗剂。Cetirizine 标记抗过敏特性,抑制过敏反应期间嗜酸性粒细胞趋化。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
De Vos, C., et al.: Ann. Allergy, 59, 278 (1987)
Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987)
Fadel, R., et al.: Clin. Allergy, 17, 373 (1987)
Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)