Ketotifen fumarate
Cat. No.：YN321397
| 产品名称: | Ketotifen fumarate |
| CAS No.: | 34580-14-8 |
| Chemical Name: | 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one-(2E)-2-butenedioate |
| Synonyms: | 富马酸酮替芬; HC 20511 fumarate |
| 分子量: | 425.50 |
| 分子式: | C₂₃H₂₃NO₅S |
| SMILES: | O=C(C1=C/2C=CS1)CC3=CC=CC=C3C2=C4CCN(C)CC/4.O=C(O)/C=C/C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ketotifen fumarate (HC 20511 fumarate) 是第二代非竞争性 H1 抗组胺剂和肥大细胞稳定剂。 |
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Sharif, N.A., Xu, S.X., and Yanni, J.M.Olopatadine (AL-4943A): Ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitisJ. Ocul. Pharmacol. Ther.12(4),401-407(1996)
Baba, A., Tachi, M., Ejima, Y., et al.Anti-allergic drugs tranilast and ketotifen dose-dependently exert mast cell-stabilizing propertiesCell Physiol. Biochem.38(1),15-27(2016)
Nishikawa, Y., Shindo, T., Ishi, K., et al.Acrylamide derivatives as antiallergic agents. III. Synthesis and structure-activity relationships of N-[4-(4-diphenylmethyl-1-piperazinyl)butyl]- and N-[4-(4-diphenylmethylene-1-piperidyl)butyl]-3-heteroarylacry lamidesChem. Pharm. Bull. (Tokyo)37(3),684-687(1989)
Miyagawa, N., Iwasaki, H., Kato, T., et al.Two pharmacological phases in antigen-induced immediate airway response in ratsBiol. Pharm. Bull.32(12),2260-2264(2008)
