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Chlorpheniramine maleate

Cat. No.:YN321443

  • CAS No. :113-92-8

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    • 产品名称: Chlorpheniramine maleate
      CAS No.: 113-92-8
      Chemical Name: γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine, 2Z-butenedioate
      Synonyms:马来酸氯苯那敏; Chlorphenamine maleate
      分子量:390.86
      分子式:C₂₀H₂₃ClN₂O₄
      SMILES:CN(C)CCC(C1=CC=C(Cl)C=C1)C2=CC=CC=N2.O=C(O)/C=C\C(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Chlorpheniramine马来酸盐是组胺H1受体拮抗剂,IC50为12 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Lish, P.M., Robbins, S.I., and Peters, E.L.Specificity of antihistamine drugs and involvement of the adrenergic system in histamine deaths in the guinea pigJ. Pharmacol. Exp. Ther.153(3),538-543(1966)

      Henson, P.M., and Cochrane, C.G.Immunological induction of increased vascular permeability. I. A rabbit passive cutaneous anaphylactic reaction requiring complement, platelets, and neutrophilsJ. Exp. Med.129(1),153-165(1969)

      Yamatake, Y., Sasagawa, S., Yanaura, S., et al.Involvement of histamine H1- and H2-receptors in induced asthmas in dogsJpn. J. Pharmacol.27(6),791-797(1977)

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