Nizatidine
Cat. No.：YN321449
| 产品名称: | Nizatidine |
| CAS No.: | 76963-41-2 |
| Chemical Name: | N'-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N-methyl-2-nitro-1,1-ethenediamine |
| Synonyms: | 尼扎替丁 |
| 分子量: | 331.46 |
| 分子式: | C₁₂H₂₁N₅O₂S₂ |
| SMILES: | CN/C(NCCSCC1=CSC(CN(C)C)=N1)=C\[N+]([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nizatidine 是一种口服有效的组胺 H2 受体 (histamine H2receptor) 拮抗剂，可用于胃溃疡的研究。在动物实验中，Nizatidine 的作用是减少胃酸的含量，并防止溃疡愈合后的复发。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Lin, T.M., Evans, D.C., Warrick, M.W., et al.Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogsJ. Pharmacol. Exp. Ther.239(2),406-410(1986)
Feldman, M., and Burton, M.E.Histamine2-receptor antagonists. Standard therapy for acid-peptic diseases. (First of two parts)N. Engl. J. Med.323(24),1672-1680(1990)
Tuskey, A., and Peura, D.The use of H2 antagonists in treating and preventing NSAID-induced mucosal damageArthritis Res. Ther.15(Suppl 3),1-7(2013)
