Famotidine
Cat. No.：YN321471
| 产品名称: | Famotidine |
| CAS No.: | 76824-35-6 |
| Chemical Name: | 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-propanimidamide |
| Synonyms: | 法莫替丁; MK-208 |
| 分子量: | 337.45 |
| 分子式: | C₈H₁₅N₇O₂S₃ |
| SMILES: | N=C(NS(=O)(N)=O)CCSCC1=CSC(NC(N)=N)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Famotidine (MK-208) 是组胺H2受体拮抗剂，可抑制胃液分泌。 |
| IC50和靶点: | |
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Gajtkowski, G.A., Norris, D.B., Rising, T.J., et al.Specific binding of 3H-tiotidine to histamine H2 receptors in guinea pig cerebral cortexNature304(5921),65-67(1983)
Kubo, N., Shirakawa, S., Kuno, T., et al.Antimuscarinic effects of antihistamines: Quantitative evaluation by receptor-binding assayJpn. J. Pharmacol.43(3),277-282(1987)
Nagaya, H., Inatomi, N., and Satoh, H.Differences in the antisecretory actions of the proton pump inhibitor AG-1749 (lansoprazole) and the histamine H2-receptor antagonist famotidine in rats and dogsJpn. J. Pharmacol.55(4),425-436(1991)
