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Olopatadine hydrochloride

Cat. No.:YN321492

  • CAS No. :140462-76-6

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    • 参考文献
    • 产品名称: Olopatadine hydrochloride
      CAS No.: 140462-76-6
      Chemical Name: 11Z-[3-(dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid, monohydrochloride
      Synonyms:盐酸奥洛他定; ALO4943A; KW4679
      分子量:373.87
      分子式:C₂₁H₂₄ClNO₃
      SMILES:O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C\CCN(C)C.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Olopatadine 盐酸盐(ALO4943A) 是组胺受体阻断剂,可作用于过敏性结膜炎。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Sharif, N.A., Xu, S.X., and Yanni, J.M.Olopatadine (AL-4943A): Ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitisJ. Ocul. Pharmacol. Ther.12(4),401-407(1996)

      Ohshima, E., Otaki, S., Sato, H., et al.Synthesis and antiallergic activity of 11-(aminoalkylidene)-6,11-dihydrodibenz[b,e]oxepin derivativesJ. Med. Chem.35(11),2074-2084(1992)

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