Olopatadine hydrochloride
Cat. No.:YN321492
产品名称: | Olopatadine hydrochloride |
CAS No.: | 140462-76-6 |
Chemical Name: | 11Z-[3-(dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid, monohydrochloride |
Synonyms: | 盐酸奥洛他定; ALO4943A; KW4679 |
分子量: | 373.87 |
分子式: | C₂₁H₂₄ClNO₃ |
SMILES: | O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C\CCN(C)C.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Olopatadine 盐酸盐(ALO4943A) 是组胺受体阻断剂,可作用于过敏性结膜炎。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Sharif, N.A., Xu, S.X., and Yanni, J.M.Olopatadine (AL-4943A): Ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitisJ. Ocul. Pharmacol. Ther.12(4),401-407(1996)
Ohshima, E., Otaki, S., Sato, H., et al.Synthesis and antiallergic activity of 11-(aminoalkylidene)-6,11-dihydrodibenz[b,e]oxepin derivativesJ. Med. Chem.35(11),2074-2084(1992)