Brompheniramine maleate
Cat. No.：YN321515
| 产品名称: | Brompheniramine maleate |
| CAS No.: | 980-71-2 |
| Chemical Name: | γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanamine, 2Z-butenedioate |
| Synonyms: | 马来酸溴苯那敏; (±) |
| 分子量: | 435.31 |
| 分子式: | C₂₀H₂₃BrN₂O₄ |
| SMILES: | O=C(O)/C=C\C(O)=O.CN(C)CCC(C1=CC=CC=N1)C2=CC=C(Br)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Brompheniramine ((±)-Brompheniramine) maleate 是一种有效的且具有口服活性的丙胺类抗组胺剂。Brompheniramine maleate 是一种选择性组胺 H1 受体 (histamine H1 receptor) 拮抗剂，Kd为 6.06 nM。Brompheniramine maleate 具有抗胆碱能，抗抑郁和镇痛作用，可用于过敏性鼻炎的研究。 |
| IC50和靶点: | [{name:"H1 Receptor:6.06 nM (Kd)"}] |
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Cusack, B., Nelson, A., and Richelson, E.Binding of antidepressants to human brain receptors: Focus on newer generation compoundsPsychopharmacology (Berl.)114(4),559-565(1994)
Högberg, T., Ulff, B., Renyi, A.L., et al.Synthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptakeJ. Med. Chem.24(12),1499-1507(1981)
