Fexofenadine hydrochloride
Cat. No.:YN321579
CAS No. :153439-40-8
产品名称: | Fexofenadine hydrochloride |
CAS No.: | 153439-40-8 |
Chemical Name: | 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-benzeneacetic acid, monohydrochloride |
Synonyms: | 盐酸非索非那定; MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride |
分子量: | 538.12 |
分子式: | C₃₂H₄₀ClNO₄ |
SMILES: | O=C(O)C(C)(C)C1=CC=C(C(O)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2)C=C1.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Fexofenadine hydrochloride (MDL-16455 hydrochloride) 是一种H1R拮抗剂,可用于季节性过敏性鼻炎和慢性特发性荨麻疹 (针对年龄大于16岁的人) 的研究。 |
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Church, M.K., and Church, D.S.Pharmacology of antihistaminesIndian J. Dermatol.58(3),219-224(2013)
Lai, W.S., Lin, Y.Y., Chu, Y.H., et al.Efficacy of fexofenadine in isolated rat tracheasRhinology51(4),376-380(2013)
Koh, S.J., Kim, J.W., Kim, B.G., et al.Fexofenadine regulates nuclear factor-κB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in miceJ. Pharmacol. Exp. Ther.352(3),455-461(2015)