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Antazoline hydrochloride

Cat. No.:YN321605

  • CAS No. :2508-72-7

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    • 产品名称: Antazoline hydrochloride
      CAS No.: 2508-72-7
      Chemical Name: 4,5-dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine, monohydrochloride
      Synonyms:Phenazoline hydrochloride
      分子量:301.81
      分子式:C₁₇H₂₀ClN₃
      SMILES:[H]Cl.C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Antazolin盐酸盐是第一代抗组胺药, 也具有抗胆碱能特性, 用于缓解鼻塞, 也用作眼药水。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Yanni, J.M., Weimer, L.K., Sharif, N.A., et al.Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugsArch. Opthalmol.11795),643-647(1999)

      Overton, J.Antistin in dermatologyBr. Med. J.1(4557),874-876(1948)

      Frommeyer, G., Sterneberg, M., Dechering, D.G., et al.Effective suppression of atrial fibrillation by the antihistaminic agent antazoline: First experimental insights into a novel antiarrhythmic agentCardiovasc. Ther.35(2),(2017)

      Olmos, G., DeGregorio-Rocasolano, N., Regalado, M.P., et al.Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptorBr. J. Pharmacol.127(6),1317-1326(1999)

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