Cinnarizine
Cat. No.：YN321607
| 产品名称: | Cinnarizine |
| CAS No.: | 298-57-7 |
| Chemical Name: | 1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)-piperazine |
| Synonyms: | 桂利嗪 |
| 分子量: | 368.51 |
| 分子式: | C₂₆H₂₈N₂ |
| SMILES: | N1(C(C2=CC=CC=C2)C3=CC=CC=C3)CCN(C/C=C/C4=CC=CC=C4)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cinnarizine是抗组胺剂和钙通道阻断剂, 促进脑血流, 用于脑中风, 创伤后脑症状, 脑动脉硬化的研究。 |
| IC50和靶点: | |
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Cohen, C.J., Spires, S., and Van Skiver, D.Block of T-type Ca channels in guinea pig atrial cells by antiarrhythmic agents and Ca channel antagonistsJ. Gen. Physiol.100(4),703-728(1992)
Arab, S.F., Düwel, P., Jüngling, E., et al.Inhibition of voltage-gated calcium currents in type II vestibular hair cells by cinnarizineNaunyn Schmiedebergs Arch. Pharmacol.369(6),570-575(2004)
Nguyen, T., Shapiro, D.A., George, S.R., et al.Discovery of a novel member of the histamine receptor familyMol. Pharmacol.59(3),427-433(2001)
Lozeva, V., Marazova, K., and Belcheva, A.Gastric histamine content and ulcer formation in rats with ethanol-induced injury. Effects of cinnarizine and flunarizineAgents Actions41 Spec No,C91-C92(1994)
