Dimaprit dihydrochloride
Cat. No.：YN321658
| 产品名称: | Dimaprit dihydrochloride |
| CAS No.: | 23256-33-9 |
| Chemical Name: | carbamimidothioic acid, 3-(dimethylamino)propyl ester, dihydrochloride |
| Synonyms: | |
| 分子量: | 234.19 |
| 分子式: | C₆H₁₇Cl₂N₃S |
| SMILES: | NC(SCCCN(C)C)=N.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dimaprit dihydrochloride 是一种选择性的组胺H2受体激动剂，它还抑制nNOS，IC50值为 49 μM。Dimaprit dihydrochloride 可刺激胃酸的分泌。 |
| IC50和靶点: | |
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| In Vivo: | |
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| Solvent & Solubility: |
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Kohno, S., Ogawa, K., Nabe, T., et al.Dimaprit, a histamine H2-agonist, inhibits anaphylactic histamine release from mast cells and the decreased release is restored by thioperamide (H3-antagonist), but not by cimetidine (H2-antagonist)Jpn. J. Pharmacol.62(1),75-79(1993)
Parsons, M.E., Owen, D.A.A., Ganellin, C.R., et al.Dimaprit-[S-[3-(N,N-dimethylamino)propyl]isothiourea] — A highly specific histamine H2-receptor agonist. Part 1. PharmacologyAgents Actions7(1),31–37(1977)
Drazen, J.M., Schneider, M.W., and Venugopalan, C.S.Bronchodilator activity of dimaprit in the guinea pig in vitro and in vivoEur. J. Pharmacol.55(3),233-239(1979)
