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Osthole

Cat. No.:YN321706

  • CAS No. :484-12-8

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    • 生物活性
    • 参考文献
    • 产品名称: Osthole
      CAS No.: 484-12-8
      Chemical Name: 7-methoxy-8-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-2-one
      Synonyms:蛇床子素; Osthol; NSC 31868
      分子量:244.29
      分子式:C₁₅H₁₆O₃
      SMILES:O=C1C=CC2=CC=C(OC)C(C/C=C(C)\C)=C2O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Osthole (Osthol) 是一种天然抗组胺药替代试剂。Osthole 可有效抑制组胺 H1受体 (histamine H1receptor) 活性。Osthole 还可抑制细胞培养物中HBV的分泌。
      IC50和靶点:
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    • Huang, R.L., Chen, C.C., Huang, Y.L., et al.Osthole increases glycosylation of hepatitis B surface antigen and suppresses the secretion of hepatitis B virus in vitroHepatology24(3),508-515(1996)

      Kuo, P.L., Hsu, Y.L., Chang, C.H., et al.Osthole-mediated cell differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway in human osteoblast cellsJ. Pharmacol. Exp. Ther.314(3),314-1290(2005)

      Zhang, Z.R., Leung, W.N., Cheung, H.Y., et al.Osthole: A review on its bioactivities, pharmacological properties, and potential as alternative medicineEvid. Based Complement. Alternat. Med.,919616(2016)

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