Nimbin
Cat. No.：YN321759
| 产品名称: | Nimbin |
| CAS No.: | 5945-86-8 |
| Chemical Name: | (2R,3aR,4aS,5R,5aR,6R,9aR,10S,10aR)-5-(acetyloxy)-2-(3-furanyl)-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-6-(methoxycarbonyl)-1,6,9a,10a-tetramethyl-9-oxo-2H-cyclopenta[b]naphtho[2,3-d]furan-10-acetic acid, methyl ester |
| Synonyms: | 宁宾 |
| 分子量: | 540.60 |
| 分子式: | C₃₀H₃₆O₉ |
| SMILES: | C[C@@]([C@@H]([C@]1(C(C=C2)=O)C)CC(OC)=O)(C3=C4C)[C@@](O[C@]3([H])C[C@@]4([H])C5=COC=C5)([H])[C@@H]([C@@]1([H])[C@]2(C)C(OC)=O)OC(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nimbin 是一种从Azadirachta中分离的中间体柠檬苦素，可防止tau聚集并增加细胞活力。Nimbin 有效抑制登革病毒 (dengue virus) 的包膜蛋白。Nimbin 具有抗炎，解热，抗真菌，抗组胺，防腐，抗氧化剂，抗癌和抗病毒特性，并可以穿越血脑屏障。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Govindachari, T.R., Suresh, G., Gopalakrishnan, G., et al.Identification of antifungal compounds from the seed oil of Azadirachta indicaPhytoparasitica26(1),109-116(1998)
Aerts, R.J., and Modue Luntz, A.J.Feeding deterrence and toxicity of neem triterpenoidsJ. Chem. Ecol.23(9),2117-2132(1997)
Akihisa, T., Noto, T., Takahashi, A., et al.Melanogenesis inhibitory, anti-inflammatory, and chemopreventive effects of limonoids from the seeds of Azadirachta indicia A. juss. (neem)J. Oleo. Sci.58(11),581-594(2009)
