YF-2 hydrochloride
Cat. No.：YN310293
| 产品名称: | YF-2 hydrochloride |
| CAS No.: | 1312005-62-1 |
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| 分子量: | 467.31 |
| 分子式: | C₂₀H₂₃Cl₂F₃N₂O₃ |
| SMILES: | O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YF-2 hydrochloride 是一种高度选择性、可透过血脑屏障的组蛋白乙酰转移酶 (histone acetyltransferase) 激动剂，能够在海马区乙酰化 H3，对 CBP，PCAF 和 GCN5 的EC50值分别为 2.75 μM，29.04 μM 和 49.31 μM，对 HDAC 无作用。具有抗肿瘤和抗阿尔滋海默症的活性。 |
| IC50和靶点: | [{name:"GCN5/PCAF:29.04 μM (EC50)"},{name: "GCN5:49.31 μM (EC50)"},{name: "CBP:2.75 μM (EC50)"}] |
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