Procyanidin B3
Cat. No.：YN310356
| 产品名称: | Procyanidin B3 |
| CAS No.: | 23567-23-9 |
| Chemical Name: | (2R,2′R,3S,3′S,4S)-2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-[4,8′-bi-2H-1-benzopyran]-3,3′,5,5′,7,7′-hexol |
| Synonyms: | 原花青素 B3 |
| 分子量: | 578.52 |
| 分子式: | C₃₀H₂₆O₁₂ |
| SMILES: | O[C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3[C@H]1C4=C5C(C[C@H](O)[C@@H](C6=CC=C(O)C(O)=C6)O5)=C(O)C=C4O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Procyanidin B3 是一种天然产物，为组蛋白乙酰转移酶 (HAT) 特异性抑制剂，可与p300的其他位点而非活性位点结合，选择性地抑制 p300 介导的 androgen 受体乙酰化。Procyanidin B3 对 HDAC 或 组蛋白甲基转移酶 (HMT) 无作用。 |
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Xie, H., Wang, J.R., Yau, L.F., et al.Catechins and procyanidins of Ginkgo biloba show potent activities towards the inhibition of β-amyloid peptide aggregation and destabilization of preformed fibrilsMolecules19(4),5119-5134(2014)
Ariga, T., Koshiyama, I., and Fukushima, D.Antioxidative properties of procyanidins B-1 and B-3 from azuki beans in aqueous systemsAgr. Biol. Chem.52(11),2717-2722(2014)
Aini, H., Ochi, H., Iwata, M., et al.Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis modelPLoS One7(5),e37728(2012)
