GSK3326595
Cat. No.：YN310045
CAS No. ：1616392-22-3
| 产品名称: | GSK3326595 |
| CAS No.: | 1616392-22-3 |
| Chemical Name: | 6-[(1-acetyl-4-piperidinyl)amino]-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-4-pyrimidinecarboxamide |
| Synonyms: | EPZ015938 |
| 分子量: | 452.55 |
| 分子式: | C₂₄H₃₂N₆O₃ |
| SMILES: | O=C(C)N1CCC(NC2=NC=NC(C(NC[C@H](O)CN3CCC(C=CC=C4)=C4C3)=O)=C2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK3326595 (EPZ015938) 是一种有效的，选择性的，可逆的蛋白精氨酸甲基转移酶 5 (PRMT5) 抑制剂，具有广谱的抗增殖活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Gerhart, S.V., Kellner, W.A., Thompson, C., et al.Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicingSci. Rep.8(1),9711(2018)
