MAK683
Cat. No.:YN310067
CAS No. :1951408-58-4
产品名称: | MAK683 |
CAS No.: | 1951408-58-4 |
Chemical Name: | N-[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine |
Synonyms: | EED inhibitor-1 |
分子量: | 376.39 |
分子式: | C₂₀H₁₇FN₆O |
SMILES: | CC1=NC=CC=C1C2=CN=C(NCC3=C4CCOC4=CC=C3F)N5C2=NN=C5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MAK683 是胚胎外胚层发育 (EED) 抑制剂,来自专利US20160176882 A1,化合物实例 2;在EED Alphascreen,LC-MS 和 ELISA 试验中的IC50值分别为 59,89,26 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Chan, H.M., Gu, X.-J., Huang, Y., et al.Triazolopyrimidine compounds and uses thereof,(2016)